Histamine’s role in fibrocystic breast disease
Suffering from breast lumps? Histamine plays an important role in Fibrocystic Breast Disease.
One of my many health scares, before my histaminosis/histamine intolerance diagnosis, was breast cancer, finally ruled out by lumpectomy. I had another cancer scare a few years later – doctors insisted on another lumpectomy, which I refused. It took me another seven years of persistent cancer fears to find the answer in a number of studies. One of the tell tale signs (that my docs should have paid attention to) was that the lumps were small, there were quite a few of them and they would completely disappear at times.
“Two mechanisms are proposed which could lead to mast cell degranulation in breast tissue. First, low progesterone levels lead to decreased intracellular cAMP levels in mast cells which enhance mast cell degranulation. Second, low progesterone levels lead to increased solubilization of breast collagen during tissue turnover. Susceptible individuals may undergo an allergic reaction to soluble collagen resulting in further mast cell degranulation. The degranulation products histamine and heparin may stimulate increased stromal proliferation and vascularization respectively. We provide evidence for the occurrence of histamine release by demonstrating an increased incidence of allergic symptoms in white women with fibrocystic breast changes.” Read the full study here.
I find it a little amusing that one of my most accurate histamine level barometers is my chest. Though I’m sure to lose your respect at this point (I promise to work hard to regain it), I must quote Lindsay Lohan’s masterpiece, ‘Mean Girls’:
Karen: Well… I’m kinda psychic. I have a fifth sense.
Cady: What do you mean?
Karen: It’s like I have ESPN or something. My breasts can always tell when it’s going to rain.
Cady: Really? That’s amazing.
Karen: Well… they can tell when it’s raining.
As soon as I feel those little lumps I know I’ve seriously fallen off the wagon and it’s high time I clamber back on up.
This doesn’t give you a get out clause from monthly self exams. I know it’s boring, so why not ask your better half to do it for you?