Hypoxia (Low Oxygen) Triggers Histamine & Mast Cell Inflammation

LOW OXYGEN
Low blood oxygen has many causes, including lack of nutrients, stress, not breathing correctly (while awake or asleep), and inflammation. Symptoms include: Shortness of breath Rapid breathing Fast heart rate Low blood pressure Confusion According to Joe Cohen at Self Hacked, our mitochondria require oxygen, and hormones are affected by a lack of it. He tells us that low oxygen can be caused, at least in part, by inflammatory cytokines which prevent oxygen from reaching the tissues.There are four types of hypoxia
Hypoxic: where there’s not enough oxygen available Hypoxemic: where cells in the body are unable to carry enough oxygen Histoxic: where cells are unable to carry enough oxygen because they’re impaired by alcohol or chemicals/drugs Stagnant: too little oxygen due to external forces (like being in a fighter jet) A voluminous amount of research tells us that hypoxia is a driving factor in many cancers, including triple negative breast cancer (the one I’m now in remission from). Cancer cells thrive in a low oxygen environment; though the tricky buggers can also proliferate in high oxygen states too. Interestingly, a study published in the journal Frontiers of Immunology found that the release of histamine in states of low oxygen actually prevents “uncontrolled degranulation” of mast cells (the process by which they release histamine). This stops the body from descending into a state of all out inflammation. But there are less extreme ways to address low oxygen.
Don’t forget to check out my favourite book Anti-Recipes – a nutrient dense cookbook full of ingredients with antihistamine and anti-inflammatory ingredients. It’s dairy/nut/gluten free, with grain free options. The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.
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“Why You May Be Suffering From Low Oxygen and Not Realize It.” Selfhacked. N.p., 23 June 2017. Web. 26 July 2017.
Möllerherm, Helene, Katja Branitzki-Heinemann, Graham Brogden, Ayssar A. Elamin, Wulf Oehlmann, Herbert Fuhrmann, Mahavir Singh, Hassan Y. Naim, and Maren Von Köckritz-Blickwede. “Hypoxia Modulates the Response of Mast Cells to Staphylococcus aureus Infection.” Frontiers. Frontiers, 24 Apr. 2017. Web. 26 July 2017.
Lee, J. J., M. Natsuizaka, S. Ohashi, G. S. Wong, M. Takaoka, C. Z. Michaylira, D. Budo, J. W. Tobias, M. Kanai, Y. Shirakawa, Y. Naomoto, A. J. Klein-Szanto, V. H. Haase, and H. Nakagawa. “Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.” Carcinogenesis.U.S. National Library of Medicine, Mar. 2010. Web. 26 July 2017.
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